Gm-csf protein
WebProduct Details Source Human GM-CSF, amino acids Ala18- Glu144 (Accession# NM_000758) was expressed in E. coli. Molecular Mass The 127 amino acid N-terminal methionylated recombinant protein has a predicted molecular mass of 14477.5 Da. WebDescription. GM-CSF Protein, Human is a hematopoietic growth factor and immune modulator. Background. Granulocyte-macrophage colony-stimulating factor (GM-CSF) …
Gm-csf protein
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WebAbstract. Granulocyte-macrophage colony-stimulating factor (GM-CSF) is a pluripotent cytokine produced by many cells in the body, which regulates normal and malignant hemopoiesis as well as innate and adaptive immunity. GM-CSF assembles and activates its heterodimeric receptor complex on the surface of myeloid cells, initiating multiple ... WebGM-CSF is a monomeric glycoprotein that functions as a cytokine —it is a white blood cell growth factor. [6] GM-CSF stimulates stem cells to produce granulocytes ( …
WebMature porcine GM-CSF shares 61%-72% amino acid sequence identity with canine, feline, human, and rat GM-CSF and 53% with mouse GM-CSF. GM-CSF exerts its biological effects through a heterodimeric receptor complex composed of GM-CSF R alpha /CD116 and the signal transducing common beta chain (CD131) which is also a component of … WebIt is also a growth factor for erythroid, megakaryocyte, and eosinophil progenitors. GM‑CSF is produced by a number of different cell types (including T cells, B cells, macrophages, mast cells, endothelial cells, fibroblasts, and adipocytes) in response to cytokine or inflammatory stimuli.
WebOct 1, 2024 · GM‐CSF derived from prostate cancer cells may in part be responsible for the induced IL1β expression as GM‐CSF is known to induce IL1β expression.33 The decreased expression of IL1β following galiellalactone treatment is in line with the observation that the STAT3 inhibitor JSI‐124 decreased IL1β in MDSCs.34 IL1β is a potent inducer ... WebGM-CSF/CSF2 Protein Molecular Weight & PI Granulocyte-macrophage colony-stimulating factor precursor (GM-CSF) (Colony-stimulating factor) (CSF) (Molgramostin) (Sargramostim) Homo sapiens (Human). The …
WebThe new PVAX1-IRES-GM/B7.1 vector was successfully modified with the GM-CSF and B7.1 molecular adjuvants via IRES linking. 38 The use of IRESs enables vectors to … iss industrial servicesWebActive Recombinant rat GM-CSF protein is an Escherichia coli Full length protein 18 to 144 aa range, >=97% purity, <= 1.000 Eu/µg endotoxin level and validated in FuncS, SDS-PAGE, HPLC. The activity … if a line bisects an angleWebRecombinant Mouse GM-CSF (Catalog # 415-ML) stimulates cell proliferation of the DA3 mouse myeloma cell line. The ED 50 for this effect is 5-30 pg/mL. SDS-PAGE View Larger 1 μg/lane of Recombinant Mouse GM-CSF was resolved with SDS-PAGE under reducing (R) conditions and visualized by silver staining, showing a single band at 14 kDa. is sinead cusack related to john cusackWebIn this study, two strains of the yeast P. pastoris were constructed, one of which produced authentic recombinant human granulocyte-macrophage colony-stimulating factor (ryGM-CSF), and the other was a chimera consisting of ryGM-CSF genetically fused with mature human apolipoprotein A-I (ApoA-I) (ryGM-CSF-ApoA-I). Both forms of the cytokine were … if a line is horizontal then its slope isWebGM-CSF: Products. GM-CSF (Granulocyte-Macrophage Colony Stimulating Factor) induces the development of monocytes, neutrophils, eosinophils, and myeloid and dermal dendritic cells. It also acts as a neutrophil and dendritic cell chemoattractant. GM-CSF promotes Th1 and Th17 cell mediated autoimmune inflammation as well as the … is sinead an irish nameWebGM-CSF (Granulocyte-Macrophage colony-stimulating factor) is a 14.6kDa hematopoietic growth factor that exists in glycosylated and non-glycosylated biologically active forms, … if a line has four feet a poem is written inWebGM-CSF inhibits neutrophil migration and enhances the functional activity of the mature end-cells. The human and murine molecules are species-specific and exhibit no cross-species reactivity. Recombinant Murine GM-CSF is a 14.2 kDa globular protein consisting of 125 amino acid residues. if a line intersects 2 concentric circles