Web14 de fev. de 2024 · 研究显示,巨噬细胞摄取的乳酸激活mTORC1信号通路,导致转录因子TFEB及其下游靶基因的表达下调,包括能够酸化溶酶体并促进蛋白质降解的ATP6V0D2 … Web21 de mar. de 2024 · EPAS1 (Endothelial PAS Domain Protein 1) is a Protein Coding gene. Diseases associated with EPAS1 include Erythrocytosis, Familial, 4 and Multiple …
NEJM:肿瘤细胞存在HIF2α基因突变-MedSci.cn
Web21 de mar. de 2024 · HIF1A (Hypoxia Inducible Factor 1 Subunit Alpha) is a Protein Coding gene. Diseases associated with HIF1A include Retinal Ischemia and Enchondromatosis, … Web重度抑郁症(mdd)的研究进展. p = 0.003),表明叶酸或者它的衍生物可能会导致抑郁症的风险升高。 5.2 creb1关联分析研究(2q34)之前一篇连锁分析在81个单向认知障碍伴随mdd的家系样本去探索精神类疾病 丁香园-细胞生物与生物信息-2024-11-24 15:18:44 inappropriate behaviour around children
Attenuating hypoxia driven malignant behavior in glioblastoma
http://www.aquaticjournal.com/article/doi/10.7541/2024.2024.261 Web5 de ago. de 2024 · Background In clear cell renal cell carcinoma, 80% of cases have biallelic inactivation of the VHL gene, leading to constitutive activation of both HIF1α and HIF2α. As HIF2α is the driver of the disease promoting tumour growth and metastasis, drugs targeting HIF2α have been developed. However, resistance is common, therefore new … WebHIF-2 alpha Antibody (PA1-16510) in ICC/IF. Immunofluorescence analysis of HIF-2 alpha was performed using HepG2 cells treated with CoCl2 (300uM for 16hrs). The cells were fixed with 4% paraformaldehyde for 10 minutes, permeabilized with 0.1% Triton™ X-100 for 15 minutes, and blocked with 2% BSA for 1 hour at room temperature. inappropriate behavior movie