WebThiolase, Kurzbezeichnung für die Acyl-CoA-Acetyltransferase (3-Ketoacyl-CoA-Thiolase), die Acyl-CoA-Verbindungen unter Mitwirkung von Coenzym A thiolytisch in Acetyl-CoA und … WebThiolase 2 is the first enzyme in the cholesterol synthesis pathway (see Figure 6 ), catalyzing the conversion of two molecules of acetyl-CoA to acetoacetyl-CoA. Hydroxymethylglutaryl …
Acetyl Coenzyme A Acetyltransferase - an overview - ScienceDirect
Acetyl-CoA-Acetyltransferase (ACAT) (auch: 3-Ketothiolase oder Thiolase II) heißen Enzyme, die die Acetylierung von Acetyl-Coenzym A und die Umkehrreaktion katalysieren. Diese Reaktionen sind zum Auf- und Abbau von Ketokörpern notwendig, aber auch in der Biosynthese der Steroide und beim Abbau mancher Aminosäuren. ACAT kommt in allen Lebewesen, und in Eukary… WebThiolase 5.3 is the dominant species in yeast cytosol (Fig. 1A). The ratio of thiolase 5.3 to thiolase 7.8 in the c*>?osol preparation is 5.4, wherea,s the same yeast, when lyscd with toluene followed by electrofocusing, resulted in a thiolasc 5.3 to … frvc baseball
Q56WD9 - UniProt
WebThiolases, also known as acetyl-coenzyme A acetyltransferases (ACAT), are an enzyme family that plays vital roles in lipid metabolism, including ACAT1, ACAT2, ACAA1, ACAA2, and HADHB. Our present... Thiolases, also known as acetyl-coenzyme A acetyltransferases (ACAT), are enzymes which convert two units of acetyl-CoA to acetoacetyl CoA in the mevalonate pathway. Thiolases are ubiquitous enzymes that have key roles in many vital biochemical pathways, including the beta oxidation pathway of fatty acid … See more Thiolases are a family of evolutionarily related enzymes. Two different types of thiolase are found both in eukaryotes and in prokaryotes: acetoacetyl-CoA thiolase (EC 2.3.1.9) and 3-ketoacyl-CoA thiolase (EC 2.3.1.16). … See more Mammalian nonspecific lipid-transfer protein (nsL-TP) (also known as sterol carrier protein 2) is a protein which seems to exist in two different forms: a 14 Kd protein (SCP-2) and … See more Most enzymes of the thiolase superfamily are dimers. However, monomers have not been observed. Tetramers are observed only in the thiolase subfamily and, in these cases, the dimers … See more • Acetyl-CoA+C-Acetyltransferase at the U.S. National Library of Medicine Medical Subject Headings (MeSH) • Overview of all the structural information available in the PDB for UniProt: P28790 (3-ketoacyl-CoA thiolase) at the PDBe-KB. See more Thioesters are more reactive than oxygen esters and are common intermediates in fatty-acid metabolism. These thioesters are made by conjugating the fatty acid with the free SH … See more In eukaryotic cells, especially in mammalian cells, thiolases exhibit diversity in intracellular localization related to their metabolic functions … See more Mitochondrial acetoacetyl-CoA thiolase deficiency, known earlier as β-ketothiolase deficiency, is an inborn error of metabolism involving isoleucine catabolism and ketone body metabolism. The major clinical manifestations of this disorder are … See more WebFigure 1: (A) The monomer subunit structure of Zoogloea ramigera thiolase (PDB ID: 1DM3). This is the common structural fold of thiolase superfamily enzymes. (B) The reaction catalyzed by coenzyme-A dependent thiolase superfamily enzymes. Thiolases are another set of enzymes that catalyze degradation of fatty acids in the β-oxidation pathway ... gifs owl